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DNA Replication
DNA replication is a fundamental cellular process that is closely linked with both patterns of genome activity and with genome variation.
Using the Repli-seq technology developed in our lab, we are generating detailed maps of replicating timing in human and mouse cells.
Featured Publications:
Science
September 7, 2012
Systematic Localization of Common Disease-Associated Variation in Regulatory DNA
Nature
September 6, 2012
An expansive human regulatory lexicon encoded in transcription factor footprints