Publications
Nature
February 19, 2015
Cell-of-origin chromatin organization shapes the mutational landscape of cancer
Nature
November 20, 2014
Conservation of trans-acting circuitry during mammalian regulatory evolution
Nature
September 6, 2012
An expansive human regulatory lexicon encoded in transcription factor footprints
Science
November 21, 2014
Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolution
Science
December 13, 2013
Exonic Transcription Factor Binding Directs Codon Choice and Affects Protein Evolution
Science
October 11, 2013
An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level
Science
September 7, 2012
Systematic Localization of Common Disease-Associated Variation in Regulatory DNA
Science
October 9, 2009
Comprehensive mapping of long-range interactions reveals folding principles of the human genome
Cell
August 15, 2013
Developmental fate and cellular maturity encoded in human regulatory DNA landscapes
Cell
September 28, 2012
Foxp3 exploits a pre-existent enhancer landscape for regulatory T cell lineage specification
Nat Genet
August 2013
DNase I-hypersensitive exons colocalize with promoters and distal regulatory elements
Nat Genet
March 2011
Chromatin accessibility pre-determines glucocorticoid receptor binding patterns
Nat Methods
January 2014
Coupling transcription factor occupancy to nucleosome architecture with DNase-FLASH
Nat Methods
April 2009
Global mapping of protein-DNA interactions in vivo by digital genomic footprinting
Nat Methods
July 2006
Genome-scale mapping of DNase I sensitivity in vivo using tiling DNA microarrays
Nat Methods
December 2004
High-throughput localization of functional elements by quantitative chromatin profiling
Nat Biotechnol
January 2014
Reduced local mutation density in regulatory DNA of cancer genomes is linked to DNA repair
Mol Cell
July 8, 2011
Transcription factor AP1 potentiates chromatin accessibility and glucocorticoid receptor binding
Genome Res
September 4, 2012
ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia
Genome Res
May 2011
Diverse gene reprogramming events occur in the same spatial clusters of distal regulatory elements
Proc Natl Acad Sci USA
April 16, 2013
Probing DNA shape and methylation state on a genomic scale with DNase I
Proc Natl Acad Sci USA
January 5, 2010
Sequencing newly replicated DNA reveals widespread plasticity in human replication timing
Proc Natl Acad Sci USA
March 10, 2009
Power of deep, all-exon resequencing for discovery of human trait genes
Proc Natl Acad Sci USA
November 30, 2004
Discovery of functional non-coding elements by digital analysis of chromatin structure
Proc Natl Acad Sci USA
March 30, 2004
Genome-wide identification of DNaseI hypersensitive sites using active chromatin sequence libraries
Dev Biol
June 15, 2012
Zebrafish globin switching occurs in two developmental stages and is controlled by the LCR
Hum Gene The
February 10, 2012
Gammaretroviral Vector Integration Occurs Overwhelmingly Within and Near DNase Hypersensitive Sites
Genome Biol
May 2011
Dynamic reprogramming of chromatin accessibility during Drosophila embryo development
Cancer Res
March 15, 2011
Contribution of inherited mutations in the BRCA2-interacting protein PALB2 to familial breast cancer
Genome Biol
December 2008
Assaying the regulatory potential of mammalian conserved non-coding sequences in human cells
Genes Dev.
March 2008
Oct4 dependence of chromatin structure within the extended Nanog locus in ES cells
